Prevention & treatment of vit B
1, B
6 & B
12 deficiencies due to increased requirements, reduced intake or absorption. Neuritis/neuropathies & polyneuritis/polyneuropathies due to vit B
1, B
6 or B
12 deficiencies, to metabolic dysfunction (eg, in diabetes) or to treatment/intoxication caused by drugs (eg, INH, D-penicillamine & other vit B
6 antagonists); as adjuvant in neuralgia, sciatica, lumbago (B
12-containing prep only); convulsions caused by drugs of the semicarbazid, thiosemicarbazid or INH-type or by convulsions due to vit B
6 deficiency; cardiomyopathies due to vit B
1 deficiency (beriberi heart); as adjuvant in post-op vomiting or radiation sickness; acute & chronic alcohol intoxication.