OA Usual dose of 30 mg once daily, increased to 60 mg once daily if necessary. RA 90 mg once daily. Gouty arthritis (acute symptomatic period) 120 mg once daily, max of 8 days.
Patients w/ hypersensitivity to NSAIDs & those w/ asthma. Patients w/ ischemic heart disease & those w/ risk factors for heart disease, HTN, hyperlipidemia, diabetes, smoking & patient w/ peripheral arterial disease. Use the lowest effective dose for the shortest duration of treatment. Discontinue if appearance of skin rash & signs of hypersensitivity occurs. Potential GI (gastric & liver) & renal toxicities. May affect the ability to drive & use machines. Not recommended in women attempting to conceive. Pregnancy & lactation.
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