Remopain

Remopain

ketorolac

Manufacturer:

PT Dexa Medica

Distributor:

Glorious Dexa Mandaya
Concise Prescribing Info
Contents
Ketorolac trometamol
Indications/Uses
Short-term management of moderate to severe post-op pain.
Dosage/Direction for Use
Max duration: Should not exceed 5 days. IV bolus must be given over no <15 sec. Short-term management of pain Initially 30 mg or 60 mg as IM, then continue w/ 15 mg or 30 mg every 6 hr if necessary. Max: 120 mg/day but dose can be increased up to 150 mg in the 1st day of treatment if needed. Moderate post-op pain 30 mg IM. Severe pain 90 mg. Single Dose: IM Adult <65 yr 60 mg. ≥65 yr w/ renal impairment &/or <50 kg 30 mg. IV Adult <65 yr 30 mg. 65 yr w/ renal impairment &/or <50 kg 30 mg. Repeated IM/IV Adult <65 yr 30 mg every 6 hr. Max: 120 mg/day. 65 yr w/ renal impairment &/or <50 kg 15 mg 6 every 6 hr. Max: 60 mg/day.
Contraindications
Hypersensitivity to ketorolac trometamol, aspirin, or other NSAIDs. Active peptic ulcer, recent GI bleeding or perforation & history of PUD or GI bleeding, hemostasis disorders, suspected or confirmed cerebrovascular bleeding, hemorrhagic diathesis, incomplete hemostasis & those at high risk of bleeding. Patients w/ history of stroke, CVA, heart attack, MI, coronary artery bypass graft, CHF NYHA II-IV. Concomitant use of other NSAIDs & probenecid. Neuraxial (epidural or intrathecal) administration. Severe renal impairment or patients at high risk of renal failure. Labor & delivery. Lactation.
Special Precautions
Cardiac, liver & renal disease. Patients receiving anticoagulant therapy & patients w/ hemophilia. Not to be used before surgery & if there are hemostasis disturbances. Discontinue if abnormality of hepatic function test occurs. Not recommended for childn <16 yr.
Adverse Reactions
Edema; HTN; pruritus, rash; nausea, dyspepsia, GI pain, diarrhea, constipation, flatulence, GI fullness, vomiting, stomatitis; purpura; cephalgia, drowsiness, dizziness, swelling; pain on inj site. Wt increase, fever, infections, asthenia; palpitations; urticaria; gastritis, rectal bleeding, belch, anorexia, appetite increase; epistaxis, anemia, eosinophilia; tremor, abnormal dream, hallucinations, euphoria, extrapyramidal symptoms, vertigo, paresthesia, depression, insomnia, nervousness, excessive thirst, dry mouth, abnormal thinking, difficult to concentrate, hyperkinesis, stupor; dyspnea, lung edema, rhinitis, cough; abnormal taste & vision; blurred vision, tinnitus, deafness; hematuria, proteinuria, oliguria, urine retention, polyuria, increased urinary frequency,
Drug Interactions
Prolonged average bleeding time w/ heparin. Decreased protein binding & potential increase in plasma conc w/ salicylate. Reduced diuretic response of furosemide. Decreased clearance w/ probenecid. Inhibition of renal clearance & increase plasma conc of lithium. Decreased clearance of methotrexate. Non-depolarizing muscle relaxants. Increased risk of renal impairment w/ ACE inhibitors especially in vol-depleted patients. Convulsion attack is occurred w/ antiepileptic drugs (phenytoin, carbamazepine). Hallucination w/ psychoactive drugs (fluoxetine, tiotixen, alprazolam). Morphine.
MIMS Class
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
ATC Classification
M01AB15 - ketorolac ; Belongs to the class of acetic acid derivatives and related substances of non-steroidal antiinflammatory and antirheumatic products.
Presentation/Packing
Form
Remopain soln for inj 30 mg/mL
Packing/Price
1 mL x 5 × 1's (P525/box)
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