Hypersensitivity to dinoprostone & prostaglandins. History of cesarean section or major uterine surgery, cephalopelvic disproportion, history of difficult labor &/or traumatic delivery, grand multiparae w/ ≥6 previous term pregnancies w/ non-vertex presentation, hyperactive or hypertonic uterine patterns, fetal distress where delivery is not imminent, in obstet emergencies where the benefit-to-risk for the fetus or mother favors surgical intervention. When vag delivery is not indicated as in herpes genitalis & patients w/ vasa previa, placenta previa or unexplained vag bleeding during pregnancy. Pregnancy (early, mid-trimester) & lactation.