Neuropathic pain w/ diabetic peripheral neuropathy Max: 100 mg tid.
CrCl at least 60 mL/min Start at 50 mg tid, may be increased to 300 mg/day w/in 1 wk.
Postherpetic neuralgia 75-150 mg bid or 50-100 tid.
CrCl at least 60 mL/min Start at 75 mg bid or 50 mg tid, may be increased to 300 mg/day w/in 1 wk. May further increase up to 300 mg bid or 200 mg tid for insufficient pain relief after 2-4 wk treatment or able to tolerate pregabalin.
Adjunctive therapy w/ partial onset seizures Adult 150-600 mg/day in 2 or 3 divided dose. Total daily dose should be started no >150 mg/day. Max: 600 mg/day.
Fibromyalgia 300-450 mg/day. Start at 75 mg bid, may be increased to 150 mg bid w/in 1 wk. May further increase to 225 mg bid for insufficient pain relief. Max: 450 mg/day.
Neuropathic pain w/ spinal cord injury 150-600 mg/day. Start at 75 mg bid, may be increased to 150 mg bid w/in 1 wk. May further increase up to 300 mg bid for insufficient pain relief after 2-3 wk treatment.
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