Resp tract & soft tissue infectionsPatient ≥40 kg 250-500 mg IM/IV 6 hrly, <40 kg 25-50 mg/kg 6-8 hrly in equally divided doses. GI & GUT infectionsPatient ≥40 kg 500 mg IM/IV 6 hrly, <40 kg 50 mg/kg/day 6-8 hrly in equally divided doses. GonorrheaAdult 500 mg IM/IV 8-12 hrly in 2 doses, repeated if necessary. Adult & childnBacterial meningitis 150-300 mg/kg 3-4 hrly in equally divided doses. Septicemia 150-200 mg/kg. Initially, administer IV for at least 3 days & continue IM 3-4 hrly.
Decreased efficacy of estrogen-containing OCs. Possible prolonged bleeding time in administration w/ coagulants. Increased risk of skin rash w/ allopurinol. Antagonism w/ chloramphenicol.
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