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Inform patients to take Sevelamer carbonate with meals and adhere to their prescribed diets. For patients using an oral medication where a reduction in the bioavailability of that medication would have a clinically significant effect on its safety or efficacy, advise the patient to take the oral medication at least one hour before or three hours after Sevelamer carbonate.
Advise patients to report new onset or worsening of existing constipation promptly to their physician.
