Sign Out
Paracetamol: Symptoms: Paleness, nausea, vomiting, anorexia, abdominal pain, metabolic acidosis and glucose metabolism disturbances. Liver damage may surface 12-48 hr after overdose. In severe cases, encephalopathy, haemorrhage, hypoglycaemia, cerebral oedema, acute renal failure and death.
Management: Immediate medical treatment even if there are no symptoms. If presented within 1 hr of poisoning, administer activated charcoal. If needed, administer IV N-acetylcysteine or oral methionine.
Orphenadrine: Symptoms: Vomiting, gastric irritation, dilated pupils, pruritus, urinary retention, tachycardia, hyperpyrexia, euphoria, hallucinations, agitation, paranoid reactions, tremor, excitement, confusion, delirium, circulatory and respiratory failure, coma and convulsions.
Management: Treatment is symptomatic and supportive.
