Adult CNS: Suspected brain metastases 0.3 mmol/kg (equiv to 0.6 mL/kg), max: up to 100 kg. Can be administered as a bolus IV inj. Equivocal scans: After 1.1 mmol/kg. 2nd bolus inj of 1.2 mmol/kg (equiv to 0.4 mL/kg) maybe of additional diagnostic value when administered w/in 20 min of the 1st inj. Whole body: 0.1 mmol/kg (equiv to 0.2 mL/kg) or 0.3 mmol/kg, occasionally (equiv to 0.6 mL/kg) up to 100 kg. Angiography 0.1 mL/kg (equiv to 0.2 mL/kg). Stenosis of abdominal & iliac arteries Up to 0.3 mmol/kg (equiv to 0.6 mL/kg). Adult & childn CNS: 0.1 mmol/kg (equiv to 0.2 mL/kg) up to 100 kg. Childn from 6 mth 0.1 mmol/kg (equiv to 0.2 mL/kg).
Consider serious, life-threatening, fatal, anaphylactoid or CV reactions or other idiosyncratic reactions especially in patients w/ known clinical hypersensitivity or history of asthma or other allergic resp disorders. Nephrogenic systemic fibrosis in patients w/ acute or severe renal impairment. Hepatorenal syndrome. Lab tests screening for renal dysfunction prior to administration. Patients suffering from epilepsy or brain lesions. May interfere serum Ca measurements w/ some colorimetric (complexometric); perform 12-24 hr after administration. Pregnancy & lactation. Infants up to 1 yr.
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