Nurtec

Nurtec

Manufacturer:

Catalent UK

Distributor:

Pfizer
Concise Prescribing Info
Contents
Rimegepant sulfate
Indications/Uses
Acute treatment of migraine w/ or w/o aura in adults. Preventive treatment of episodic migraine in adults who have at least 4 migraine attacks per mth.
Dosage/Direction for Use
Acute treatment of migraine 75 mg once daily. Prophylaxis of migraine 75 mg every other day. Max: 75 mg daily.
Administration
May be taken with or without food: Place tab on or under the tongue to disintegrate.
Contraindications
Special Precautions
Hypersensitivity reactions, including dyspnea & rash; discontinue if it occurs. Avoid the next dose w/in 48 hr when concomitantly administered w/ moderate CYP3A4 inhibitors. Not recommended for concomitant use w/ strong inhibitors & strong or moderate inducers of CYP3A4. Medication overuse headache. Not recommended in patients w/ severe hepatic impairment; ESRD (CrCl <15 mL/min). Severe renal impairment. Patients on dialysis. Avoid during pregnancy & lactation. Childn <18 yr.
Drug Interactions
Increased plasma conc w/ CYP3A4 inhibitors (eg, clarithromycin, itraconazole, ritonavir). May increase exposure w/ medicinal products that moderately inhibit CYP3A4 (eg, diltiazem, erythromycin, fluconazole). Decreased plasma concw/ CYP3A4 inducers. May increase plasma conc w/ inhibitors of P-gp & BCRP efflux transporters.
MIMS Class
Antimigraine Preparations
ATC Classification
N02CD06 - rimegepant ; Belongs to the class of calcitonin gene-related peptide (CGRP) antagonists preparations. Used to relieve migraine.
Presentation/Packing
Form
Nurtec orally disintegrating tab 75 mg
Packing/Price
2's;8's
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