Noren

Noren

norepinephrine

Manufacturer:

BCWorld Pharm

Distributor:

JustRight Healthcare
Concise Prescribing Info
Contents
Norepinephrine bitartrate
Indications/Uses
Secondary treatment of acute hypotension or shock according to different diseases (shock due to MI, & septicemia caused by shock, anaphylactic shock, hypotension or shock, according to the decreased circulating blood vol, acute hypotension during anesth) & cardiac arrest.
Dosage/Direction for Use
Acute hypotension or shock Individualized dose. IV infusion at 2-3 mL/min. Maintenance: 0.5-1 mL/min. Cardiac arrest Inj IV in case of acute hypotension or shock after retaining valid heart rate & ventilation while cardiac resuscitation.
Contraindications
Patients w/ low BP due to lack of blood vol (except for emergency situations to maintain cerebral perfusion); high BP, hyperthyroidism, pheochromocytoma, pulmonary heart disease, severe arrhythmia; anesthesized fingers, toes, nose. Renal dysfunction. Pregnancy.
Special Precautions
Hypersensitivity w/ Na sulfite. Patients w/ cocaine poisoning, ventricular tachycardia, atherosclerosis, heart disease, bradycardia, coronary, mesenteric, peripheral vascular thrombosis, hypotension due to MI, Prinzmetal angina. Do not use as substitute for blood or fluids. May cause an excessive increase in BP & acute pulmonary edema action, arrhythmia, cardiac arrest may occur. Frequently check BP & administration rate to avoid high increase in BP. May cause remarkable peripheral & internal vasoconstriction, decrease in renal perfusion & urea emission, decrease in blood vol despite normal BP, tissue hypoxia, metabolic acidosis; consider using w/ blood vol replacement. Lactation. Elderly.
Adverse Reactions
Ischemic injury due to potent vasoconstrictor action & tissue hypoxia; cardiogenic shock, arrhythmia, bradycardia, probably as a reflex result of a rise in BP, stress cardiomyopathy; anxiety, transient headache; resp difficulty; extravasation necrosis at inj site.
Drug Interactions
Increased risk of ventricular tachycardia or fibrillation w/ cyclopropane & halothane anesth. May cause severe, prolonged HTN w/ MAOIs or antidepressants of triptyline or imipramine types.
MIMS Class
Vasoconstrictors
Presentation/Packing
Form
Noren 1 mg/mL soln for inj
Packing/Price
4 mL x 10 × 1's
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