Nebilet Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Nebivolol HCl

Indications/Uses

Treatment of essential HTN & stable mild & moderate chronic heart failure in addition to standard therapies in elderly patients.

Click to view Nebilet detailed prescribing information

Dosage/Direction for Use

HTN Adult 5 mg once daily. In combination w/ other antihypertensive agents 5 mg plus hydrochlorothiazide 12.5-25 mg. Elderly >65 yr Start at 2.5 mg daily. May be increased to 5 mg daily. Chronic heart failure Initially 1.25 mg once daily, increase at interval of 1-2 wk based on patient's tolerability to 2.5, 5 & 10 mg once daily.

Click to view Nebilet detailed prescribing information

Overdosage

View Nebilet overdosage for action to be taken in the event of an overdose.

Administration

May be taken with or without food: Preferably taken at the same time each day.

Contraindications

Hypersensitivity. Liver insufficiency or impairment. Acute heart failure, cardiogenic shock or episodes of heart failure decompensation. Sick sinus syndrome including SA block; 2nd- & 3rd-degree heart block (w/o a pacemaker); history of bronchospasm & bronchial asthma; untreated pheochromocytoma; metabolic acidosis; bradycardia (heart rate <60 bpm); hypotension (systolic BP <90 mmHg); severe peripheral circulatory disturbances.

Click to view Nebilet detailed prescribing information

Special Precautions

Concomitant use w/ anesth. Untreated CHF, ischemic heart disease. Peripheral circulatory disorders (Raynaud's disease or syndrome, intermittent claudication); 1st-degree heart block; Prinzmetal's angina. DM, hyperthyroidism, COPD, history of psoriasis. May increase sensitivity to allergens & severity of anaphylactic reactions. Avoid abrupt w/drawal. Severe renal impairment. Galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. May impair ability to drive or operate machinery. Pregnancy & lactation. Childn & adolescent. Elderly >75 yr.

Click to view Nebilet detailed prescribing information

Use In Pregnancy & Lactation

Click to view Nebilet detailed prescribing information

Adverse Reactions

Headache, dizziness, paresthesia; dyspnea; constipation, nausea, diarrhea; tiredness, edema; bradycardia.

Click to view Nebilet detailed prescribing information

Drug Interactions

Class I antiarrhythmics & amiodarone, verapamil or diltiazem type Ca antagonist, centrally-acting antihypertensives, anesth, insulin & oral antidiabetic drugs. Digitalis glycosides; dihydropyridines; TCAs, barbiturates, phenothiazines, sympathicomimetic agents. CYP2D6 inhibitors, cimetidine, nicardipine.

Click to view Nebilet detailed prescribing information

Storage

View Nebilet storage conditions for details to ensure optimal shelf-life.

Description

View Nebilet description for details of the chemical structure and excipients (inactive components).

Action

View Nebilet mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Beta-Blockers

ATC Classification

C07AB12 - nebivolol ; Belongs to the class of selective beta-blocking agents. Used in the treatment of cardiovascular diseases.

Regulatory Classification

Presentation/Packing

Form

Nebilet tab 5 mg

Packing/Price

30's (P19.5/tab)

Nebilet

nebivolol

Manufacturer:

A. Menarini

Distributor:

Zuellig