IV bolus inj over 5 min or IV infusion over 15-30 min.
Adult Dose range: 1.5-6 g daily in 3 divided doses. Usual dose: 500 mg-1 g IV every 8 hr.
Childn >50 kg Adult dose.
Infant & childn >3 mth & up to 12 yr 10-40 mg/kg IV every 8 hr.
Febrile episodes in neutropenic patients Adult 1 g every 8 hr.
Childn 20 mg/kg every 8 hr.
Meningitis/cystic fibrosis Adult g every 8 hr.
Childn 40 mg/kg every 8 hr.
Infections caused by Pseudomonas aeruginosa Adult At least 1 g every 8 hr. Max: 6 g daily in 3 divided doses.
Childn At least 20 mg/kg every 8 hr. Max: 120 mg/kg daily in 3 divided doses.
Renal impairment CrCl 26-50 mL/min 1 u dose every 12 hr,
10-25 mL/min ½ u dose every 12 hr,
<10 mL/min ½ u dose every 24 hr.
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