Adult 100 mg IV 1-3 wkly. Total dose: 1,000 mg in 10 doses. Repeat if needed not >3x wkly. Repletion treatment of Fe deficiency in hemodialysis patients 100 mg by slow IV inj over 5 min or IV infusion over at least 15 min. Min cumulative dose: 1,000 mg over 10 consecutive dialysis sessions.
Discontinue therapy in patients w/ evidence of Fe overload. Periodic monitoring of hematologic & hematinic parameters (Hb, hematocrit, serum ferritin & transferrin saturation). Serum Fe values may be reliably obtained 48 hr after IV dosing. Hypersensitivity reactions, hypotension. Pregnancy & lactation. Childn. Elderly.
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