Antihyperlipidemic agent.
Pharmacology: Gemfibrozil is a lipid-regulating agent which lowers elevated serum lipids primarily by decreasing serum triglycerides and total serum cholesterol. It reduces elevated plasma concentrations of triglycerides and to a somewhat smaller extent, elevated plasma concentrations of cholesterols, the effect is particularly evident in a reduction of elevated concentrations of very low density lipoproteins. It is also recommended by the American Diabetes Association for type II B dyslipidemias ie, high triglycerides, high LDL, low HDL as first-line therapy.