Hypersensitivity to the active substance or to any of the excipients.
Must not be used in women with childbearing potential.
Active or past history of venous thromboembolic events (VTE), including deep vein thrombosis, pulmonary embolism and retinal vein thrombosis.
Hepatic impairment, including cholestasis.
Severe renal impairment.
Unexplained uterine bleeding.
Raloxifene should not be used in patients with signs or symptoms of endometrial cancer, as safety in this patient group has not been adequately studied.