Should be taken with food: Take w/ meals or w/in 30 min after meals or bedtime snack.
Contraindications
Hyperkalemia or conditions predisposing to hyperkalemia. Chronic renal failure, uncontrolled DM, acute dehydration, strenuous physical exercise in unconditioned individuals, adrenal insufficiency, extensive tissue breakdown; PUD & renal insufficiency (GFR <0.7 mL/kg/min). Patients in whom there is cause for arrest or delay in tab passage through GI tract eg, those w/ delayed gastric emptying, esophageal compression, intestinal obstruction/stricture or use of anticholinergics. K-sparing agent (eg, triamterene, spironolactone or amiloride).
Hyperkalemia & cardiac arrest. Avoid use in chronic renal failure or other condition which impairs K excretion eg, severe myocardial damage or heart failure. Concomitant use w/ diuretics & digitalis prep. Tarry stools or other evidence of GI bleeding may be noticed.
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