IV/IM Patient ≥13 yr 1 g once daily.
Patient 3 mth-12 yr 15 mg/kg bid. Max: 1 g daily. IV should be infused over 30-min period. Usual duration of therapy: 3-14 days depending on type of infection & causative pathogen(s).
Adult Prophylaxis of surgical site infection following elective colorectal surgery 1 g as a single IV dose given 1 hr prior to surgical incision.
Advanced renal insufficiency (CrCl ≤30 mL/min/1.73 m2) including those on hemodialysis 500 mg daily.
Patient on hemodialysis 500 mg given w/in 6 hr prior to hemodialysis, then a supplementary dose of 150 mg following the hemodialysis session. No supplementary dose is needed if given at least 6 hr prior to hemodialysis.
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