Immunosin

Immunosin

inosine pranobex

Manufacturer:

UNILAB, Inc

Distributor:

UNILAB, Inc
Concise Prescribing Info
Contents
Inosine dimepranol acedoben
Indications/Uses
As immunomodulator for the management of patients w/ immunodepression suffering from viral infections eg, subacute sclerosing panencephalitis (SSPE), varicella, herpes simplex type 1 & 2. Management of recurrent herpes simplex type 1 & 2. Adjunct in the treatment of genital warts.
Dosage/Direction for Use
Tab Adult 2 tab every 6 hr for 5-14 days. Herpes simplex 1 g every 6 hr for 7-14 days. Genital warts 1 g every 8 hr for 14-28 days. Adult & childn w/ SSPE 50-100 mg/kg/day in divided doses every 4 hr. Syr Adult & elderly 20 mL every 6-8 hr. Childn 7-12 yr 5 mL every 4-6 hr; 3-6 yr 3 mL every 4-6 hr; 1-2 yr 2 mL every 4-6 hr; 7-12 mth 1.5 mL every 4-6 hr; birth to 6 mth 1 mL every 4-6 hr. Duration of treatment: 5-14 days.
Administration
Should be taken with food.
Contraindications
Hypersensitivity. Gout or elevated uric acid blood levels.
Special Precautions
Patients w/ history of gout, hyperuricemia, urolithiasis, nephrolithiasis; renal impairment. Regularly monitor serum & urine conc of uric acid, blood count, liver & renal functions if administered continuously ≥3 mth. Pregnancy & lactation.
Adverse Reactions
Nausea w/ or w/o vomiting, abdominal pain, epigastric discomfort, diarrhea, constipation. Pruritus/itching, skin rashes, exacerbation of allergic rash. Headache, vertigo, fatigue, malaise, nervousness, drowsiness, insomnia/sleeplessness. Elevation of transaminases, alkaline phosphatase or BUN levels. Polyuria. Arthralgia, cold-like reaction (sinusitis).
Drug Interactions
Increase plasma level of zidovudine. Xanthine oxidase inhibitors or uricosuric agents, including diuretics.
MIMS Class
Antivirals
ATC Classification
J05AX05 - inosine pranobex ; Belongs to the class of other antivirals. Used as a direct acting antiviral in the systemic treatment of viral infections.
Presentation/Packing
Form
Immunosin syr 250 mg/5 mL
Packing/Price
60 mL x 1's (P289/bottle)
Form
Immunosin tab 500 mg
Packing/Price
24's (P708/pack, P29.5/tab)
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