Immunocep

Immunocep

mycophenolic acid

Manufacturer:

Bafna Pharma

Distributor:

Rinon Care
Concise Prescribing Info
Contents
Mycophenolate mofetil
Indications/Uses
Prevention of graft rejection, heart or liver w/ other immunosuppressants. Prevent organ rejection w/ ciclosporin & corticosteroids.
Dosage/Direction for Use
Kidney transplants Adult 1 g bid, starting w/in 72 hr after the transplant. Childn between 2 & 18 yr Calculate dose depending on height & wt. Heart transplants Adult 1.5 g bid, starting w/in 5 days following transplant. Liver transplants Adult Given as an infusion (drip into vein) for the 1st 4 days after the transplant, before the patient is switched to 1.5 g bid as soon as it can be tolerated.
Administration
Should be taken on an empty stomach: Do not crush.
Contraindications
Hypersensitivity to mycophenolate mofetil or mycophenolic acid. Hereditary deficiency of hypoxanthine guanine phosphoribosyl-transferase (HGPRT) eg, Lesch-Nyhan syndrome or Kelley-Seegmiller syndrome. Concomitant use w/ azathioprine, cholestyramine, colestipol or another medicine that contains mycophenolate or mycophenolic acid; norfloxacin & metronidazole.
Special Precautions
Allergies to medicines, foods, or other substances. Patients w/ immune system problems or taking another medicine that may suppress the immune system. Stomach or bowel problems (eg, ulcers), or kidney problems. Patients w/ fair skin or has personal or family history of skin cancer, blood cancer (eg, lymphoma), or other blood problems. Scheduled for vaccination. Close contact w/ a person who has shingles, another type of herpes infection or cytomegalovirus (CMV) infection. Taking any prescription or nonprescription medicine, herbal prep, or dietary supplement. Pregnancy & lactation. Not recommended for childn after heart or liver transplant.
Adverse Reactions
Infection, asthma, metabolic acidosis, pleural effusion, oral candidiasis, resp tract infection, UTI, herpes simplex infection, viremia, systemic CMV disease, nausea, vomiting, tachycardia, edema, hypokalemia, hypotension, HTN, diarrhea, fever, constipation, dyspepsia, wt gain, headache, weakness, myalgia, anxiety, leg cramps, drowsiness, paresthesia, tremor, dyspnea, chest pain, leukopenia, depression, thrombocytopenia, cough, anemia, pain, rhinitis, acne vulgaris, peripheral edema, hyperlipidemia, hypertonia, hypercholesterolemia, pulmonary disease, dermatological disease, abdominal pain, myasthenia, increased serum creatinine, back pain, hypervolemia, increased serum AST, CV disorder, increased serum ALT, increased LDH, hyperuricemia, sinusitis, chills, & flatulence.
Drug Interactions
May increase blood levels w/ acyclovir or ganciclovir; probenecid. May decrease blood levels w/ antacids containing Mg or Al hydroxide; PPIs eg, lansoprazole, pantoprazole, & omeprazole; cholestyramine; cyclosporine; sevelamer & other Ca free phosphate binders; norfloxacin & metronidazole; ciprofloxacin, amoxicillin + clavulanic acid, & rifampin. May decrease effectiveness of OCs
MIMS Class
Immunosuppressants
ATC Classification
L04AA06 - mycophenolic acid ; Belongs to the class of selective immunosuppressive agents. Used to induce immunosuppression.
Presentation/Packing
Form
Immunocep tab 500 mg
Packing/Price
10's
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