Patients w/ history of micturition syncope. Marked lowering of BP & syncope w/ 1st few doses of therapy. Intraoperative floppy iris syndrome (IFIS) during cataract surgery. Small but statistically significant decreased in hematocrit, Hb, WBC, total protein & albumin. Concomitant use of phosphodiesterase-5 (PDE5) inhibitors. May affect ability to drive or operate machinery. Pregnancy & lactation. Childn.
Possible significant hypotension w/ other antihypertensives (eg, Ca antagonists), PDE-5 inhibitors. Greater appearance of dizziness & other dizziness-related AR w/ ACE inhibitors & diuretics.
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