Uncomplicated UTI 250 mg once daily for 3 days. Other susceptible infections 250-500 mg once daily or bid for 10-14 days. Chronic bacterial prostatitis 500 mg daily in a 28-day course of treatment. Complicated skin infections & hospital-acquired pneumonia 750 mg once daily for 7-14 days. Community-acquired pneumonia or acute bacterial sinusitis 750 mg once daily for 5 days.
View Floxwin overdosage for action to be taken in the event of an overdose.
Administration
May be taken with or without food: Ensure adequate fluid intake.
Contraindications
Hypersensitivity to levofloxacin or any other quinolone. Patients w/ epilepsy; history of tendon disorder related to fluoroquinolone administration. Pregnancy & lactation.
Concomitant use w/ antidiabetic agent may cause disturbances of blood glucose, including hyperglycemia & hypoglycaemia; careful monitoring of blood glucose is recommended. Concomitant administration w/ NSAIDs may increase risk of CNS stimulation & convulsive seizures. Patients w/ known aortic aneurysm or who are at great risk for aortic aneurysms. Pregnancy & lactation. Not indicated for ped patients <18 yr. Elderly.
Confusion, difficulty of breathing, irregular heartbeat, palpitations or chest pain, joint, muscle or tendon pain, nightmares, changes in thought process, redness, blistering, peeling or loosening of skin, including inside the mouth, seizure, severe or watery diarrhea, skin rash, itching, swelling of face or neck, tremor or restlessness, vision changes, vomiting. Constipation or diarrhea, difficulty in sleeping, dizziness or drowsiness, headache, intestinal gas or bloating, nausea or stomach upset.
Interference of GI absorption resulting in lower systemic levels w/ antacids containing Mg, Al, as well as sucralfate, metal cations eg, Fe, & multivit prep w/ Zn or didanosine.
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