SC Prophylaxis of venous thromboembolic disease in surgical patients 0.2-0.4 mL once daily. For general surgery, 1st inj should be given 2 hrs before surgical procedure.
Orthopedic surgery 0.4 mL once daily initiated 12 hr preop.
Prophylaxis of venous thromboembolic disease in medical patients 0.4 mL once daily for 6 days & continued for max of 14 days until the return of full ambulation. DVT w/ or w/o pulmonary
embolism 150 anti-Xa IU/kg daily or 100 anti-Xa IU/kg bid.
Complicated thromboembolic disorders 100 anti-Xa IU/kg bid.
Unstable angina & non-Q-wave MI 100 anti-Xa IU/kg every 12 hr + oral aspirin 100-325 mg once daily for 2-8 days.
Prevention of thrombus formation in extra corporeal circulation during hemodialysis 100 anti-Xa IU/kg.
Patients w/ high risk of hemorrhage 50 anti-Xa IU/kg for double vascular access or 75 anti-Xa IU/kg for single vascular access.
Severe renal impairment 2000 anti-Xa IU once daily (prophylactic), 100 anti-Xa IU/kg once daily (therapeutic).
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