Losartan: Decreased conc of losartan w/ rifampin. Decreased active metabolite conc & increased losartan conc w/ fluconazole. May lead to increase in serum K w/ K-sparing diuretics, K supplements or salt substitutes containing K. Reduced excretion of lithium. May result in further renal function deterioration in some patients w/ compromised renal function & may diminish antihypertensive effect of losartan w/ NSAIDs including selective COX-2 inhibitors.
C09DB06 - losartan and amlodipine ; Belongs to the class of angiotensin II receptor blockers (ARBs) and calcium channel blockers. Used in the treatment of cardiovascular disease.
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