Epovax Special Precautions

Hematocrit should be checked periodically during treatment (once a week during the primary period, once every two weeks during maintenance phase) to avoid formation of excessive red cells (ensure which to be less than 36 vol %). Administration shall be discontinued provisionally, if excessive red cells are formed.
Diet shall be adjusted because application of this drug may cause slight elevation of serum potassium sometimes. Dosage shall be adjusted under the guidance of doctors if elevation of serum potassium occurs.
For patients with myocardial infarction, pulmonary infarction and cerebral infarction, and patients with allergic history and allergic tendency, use of the drug shall be careful.
During the treatment, demand of iron will increase because of effective hemopoiesis. Usually, the concentration of serum iron will decrease. Iron preparation shall be supplied everyday if serum ferritin is lower than 100 mg/mL or transferrin saturation is lower than 20%.
Deficiency of folic acid or vitamin B12 will lower curative effect of the drug, so does serious excessive aluminum.
Athlete shall use carefully.
Use in Children: No data to support the medication security for prematures, newborns and infants.
Use in Elderly: Elderly patients shall monitor blood pressure and hematocrit, and adjust dosage and frequency appropriately.