Hypersensitivity to any component of the product formulation, such as etanercept, sucrose, sodium chloride, L-arginine hydrochloride, sodium phosphate monobasic dihydrate, sodium phosphate dibasic dihydrate, and water for injection.
Sepsis or risk of sepsis (see Precautions and Adverse Reactions).
Treatment with Etanercept (Enbrel) should not be initiated in patients with serious active infections, including chronic or localized infections.