2-4.5 mg/kg/day IV for 10 days repeated at intervals of 4 wk or 250 mg/m2 daily for 5 days, repeated at intervals of 3 wk. Malignant melanoma 850 mg/m2 IV infusion at 3 wk interval. Hodgkin's disease 150 mg/m2/day for 5 days in combination w/ other effective drugs. May be repeated every 4 wk or 375 mg/m2/day in combination w/ other antineoplastic agents, to be repeated every 15 days.
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