Treatment & relief of acid-related dyspepsia, GERD, NSAID-associated ulceration, Zollinger-Ellison syndrome & management of PUD. Prophylaxis of acid aspiration during general anesth.
GERD 20-40 mg once daily for 4 wk. Dyspepsia 10-20 mg daily for 2-4 wk. PUD 20 mg daily as single dose or 40 mg in severe case. NSAID-associated ulceration 20 mg daily. Zollinger-Ellison syndrome 40 mg once daily. Acid aspiration prophylaxis during general anesth 40 mg in the evening before surgery & a further 40 mg 2-6 hr before the procedure.
May reduce absorption of ampicillin esters, Fe salts or ketoconazole. Delayed elimination & increased blood conc w/ anticoagulants (coumarin or indadione-derivative), diazepam or phenytoin. Increased leukopenic &/or thrombocytopenic effects w/ bone marrow depressants.
A02BC02 - pantoprazole ; Belongs to the class of proton pump inhibitors. Used in the treatment of peptic ulcer and gastro-oesophageal reflux disease (GERD).