Doxar

Doxar

losartan

Manufacturer:

Hizon Laboratories, Inc

Distributor:

PNSV Asia
Concise Prescribing Info
Contents
Losartan K
Indications/Uses
Management of HTN particularly in patient who develop cough w/ ACE inhibitors & reduce the risk of stroke in patient w/ left ventricular hyperthropy. Diabetic nephropathy.
Dosage/Direction for Use
HTN 50 mg once daily, may be increased to 100 mg once daily as single dose or in 2 divided doses. Patient w/ possible intravascular vol depletion & patient w/ hepatic impairment Initially 25 mg once daily. Elderly >75 yr & patient w/ moderate to severe renal impairment (CrCl <20 mL/min) Initially w/ 25 mg once daily.
Administration
May be taken with or without food.
Contraindications
Special Precautions
Intravascular vol depletion, bilateral renal artery stenosis, renal & hepatic impairment, hyponatremia, renal insufficiency vol depletion or concomitant use w/ diuretics. Monitor serum K levels in type 2 DM w/ proteinuria, hyponatremia. Lactation.
Adverse Reactions
Dizziness. Headache, fatigue, neutropenia, asthenia, upper resp tract infection, back pain, GI disturbances, dose-related orthostatic hypotension. Hyperkalemia.
Drug Interactions
May cause hyperkalemia w/ K supplements or K-sparing diuretics. Enhances BP-lowering action of other antihypertensives.
MIMS Class
Angiotensin II Antagonists
ATC Classification
C09CA01 - losartan ; Belongs to the class of angiotensin II receptor blockers (ARBs). Used in the treatment of cardiovascular disease.
Presentation/Packing
Form
Doxar filmtab 50 mg
Packing/Price
100's (P1,230.52/pack)
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