Alternative prophylaxis to aspirin in patients w/ atherosclerosis who are at risk of thromboembolic disorders eg, MI, peripheral arterial disease, & stroke.
Recent MI, recent stroke or established peripheral arterial disease 75 mg once daily. Patient w/ acute coronary syndrome (unstable angina/non-Q wave MI) Initially 300 mg as single loading dose & then continued at 75 mg once daily. Initiate aspirin 75-325 mg once daily & continued in combination w/ clopidogrel.
Patients at risk of increased bleeding from trauma, surgery, or other pathological conditions. Patients who have lesions w/ a susceptibility to bleed eg, ulcers. Use w/ drugs that might induce lesions. Severe hepatic or renal impairment. Pregnancy & lactation. Childn.
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