Co-Ivyzar Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Irbesartan, hydrochlorothiazide

Indications/Uses

Treatment of essential HTN & for adults who have HTN that is not adequately controlled by irbesartan or hydrochlorothiazide alone.

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Dosage/Direction for Use

HTN 150 mg/12.5 mg-300 mg/12.5 mg once daily.

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Overdosage

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Administration

May be taken with or without food: Take in the morning to avoid sleep interruption due to diuresis.

Contraindications

Hypersensitivity. Pregnancy.

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Special Precautions

Hepatic & renal impairment. Lactation. Elderly.

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Use In Pregnancy & Lactation

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Adverse Reactions

Irbesartan: Dizziness & headache; orthostatic hypotension; GI disturbances, fatigue, muscle & joint pains, congestion, hyperkalemia, back pain, vertigo, migraine, cough, acute pancreatitis & increase in liver enzymes; hypersensitivity reactions eg, rash, urticaria, pruritus & angioedema.

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Drug Interactions

Irbesartan: CYP2C9 substrates/inhibitors eg, sulfaphenazole, tolbutamide & nifedipine. Hydrochlorothiazide: Digitalis glycosides; drugs that prolong QT interval eg, astemizole, terfenadine, halofantrine, pimozide & sotalol; neuromuscular blockers eg, atracurium; corticosteroids, corticotropin, β₂-agonists eg, salbutamol, carbenoxolone, amphotericin B or reboxetine; NSAIDs, pressor amines eg, noradrenaline, lithium, allopurinol, tetracyclines.

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Storage

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Action

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MIMS Class

Angiotensin II Antagonists / Diuretics

ATC Classification

C09DA04 - irbesartan and diuretics ; Belongs to the class of angiotensin II receptor blockers (ARBs) in combination with diuretics. Used in the treatment of cardiovascular disease.

Regulatory Classification

Presentation/Packing

Form

Co-Ivyzar tab 150 mg/12.5 mg

Packing/Price

100's (P25/tab)

Form

Co-Ivyzar tab 300 mg/12.5 mg

Packing/Price

100's (P40/tab)

Co-Ivyzar

irbesartan + hydrochlorothiazide

Manufacturer:

Interphil

Distributor:

Interphil