Infections due to staphylococci resistant benzylpenicillin including infection of skin & soft tissues, bones & joints, resp tract, urinary tract; otitis media, endocarditis septicemia & meningitis. For mixed streptococcal infections when the staphylococci are penicillin resistant. Prophylaxis of staphylococcal infections during major surgical procedures particularly in cardiothoracic & orthopaedic surgery.
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