IMAdult 50-150 mg (1-3 mL) repeated if necessary w/ 2-3 days interval. May inj 24-48 hr following 1st inj. Max: 400 mg for 4 inj & should not be >2 wk. Elderly Max: 100 mg.
Possible development of neuroleptic malignant syndrome. Patients w/ preexisting organic brain syndrome, mental retardation, opiate & alcohol abuse; convulsion & advanced hepatic disease; hypokalemia, hypomagnesemia or genetic predisposition; & history of CV disorders. May modify insulin & glucose response. May cause QT prolongation. Venous thromboembolism. Avoid concomitant use w/ other antipsychotics. Determine serum liver function. Not use for treatment of dementia-related behavioral disturbances. May impair ability to drive or operate machinery. Pregnancy & lactation. Not recommended for childn. Elderly (w/ dementia & risk for cerebrovascular adverse events).
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