Prophylaxis of thromboembolic events 75 mg once daily. Management of acute coronary syndromes including unstable angina & non-Q wave MI 300 mg as single loading dose followed by 75 mg once daily.
History of bleeding; risk of increased bleeding from recent trauma, surgery or other pathological conditions. Recent transient ischemic attack or stroke when combined w/ aspirin. Discontinue use 5-7 days prior to elective surgery. Patients who have lesion w/ a propensity to bleed. Concomitant use w/ warfarin, aspirin & drugs that might induce GI lesions.