All manifestation responsive to the neurotropic analgesic and detoxifying effects of Vitamin B1, B6 and B12. Toxic and degenerative disorders of the nerve fibers, neuritis and polyneuritis of varied etiologies (beriberi, pregnancy, diabetes, chronic alcoholism, drug intoxication, excessive consumption of tobacco), neuralgia, sciatica, lumbago, idiopathic and senile tremors, Parkinson's disease, Korsakoffs psychosis and delirium tremens. Toxicity of other origins: vomiting of pregnancy, radiation sickness, alcoholism and its cerebral, hepatic and cardiac complications during withdrawal therapy of alcoholism and liver diseases.