Hypersensitivity to penicillins. History of allergy & GI disease (colitis). Superinfections may occur w/ prolonged use. Risk of Clostridium difficile associated diarrhea. Concurrent use w/ potent diuretics. Monitor prothrombin time in patients w/ renal or hepatic impairment, poor nutritional state, those receiving a protracted course of antibacterial therapy & previously stabilized on anticoagulant therapy. False +ve reaction w/ Cu reduction tests. Discontinue if seizures occur. Pregnancy & lactation.
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