Boostrix

Boostrix

Manufacturer:

GlaxoSmithKline

Distributor:

Zuellig
Concise Prescribing Info
Contents
Diphtheria, tetanus & acellular pertussis (adsorbed, reduced antigen)
Indications/Uses
Booster vaccination against diphtheria, tetanus & pertussis for individuals from ≥4 yr. Passive protection against pertussis in early infancy following maternal immunisation during pregnancy. Management of tetanus prone injuries in persons who have previously received primary vaccination series.
Dosage/Direction for Use
Deep IM 0.5 mL as a single dose in deltoid region. Pregnant women Can be administered during 2nd or 3rd trimester in accordance w/ official recommendations. Adult & adolescent w/ unknown or incomplete vaccination status 2 additional doses at 1 & 6 mth after 1st dose is recommended. Repeat vaccination Perform intervals in accordance w/ official recommendations (generally 10 yr).
Contraindications
Hypersensitivity or to subjects showing signs of hypersensitivity after previous administration of diphtheria, tetanus or pertussis vaccines. Encephalopathy of unknown etiology occurring w/in 7 days following previous pertussis-containing vaccination. Transient thrombocytopenia or neurological complications following an earlier immunization against diphtheria &/or tetanus.
Special Precautions
Do not administer IV. Postpone vaccination in subjects suffering from acute severe febrile illness. Subsequent dose of vaccine should be carefully considered if any of the following occur: Temp ≥40°C w/in 48 hr of unidentifiable cause; collapse or shock-like state (hypotonic-hyporesponsive episode) w/in 48 hr of vaccination; persistent, inconsolable crying lasting ≥3 hr w/in 48 hr of vaccination; convulsion w/ or w/o fever w/in 3 days of vaccination. Progressive neurological disorders including infantile spasms, uncontrolled epilepsy or progressive encephalopathy. Thrombocytopenia or bleeding disorders (in accordance w/ official recommendations, vaccine may need to be administered subcutaneously). Immunosuppressed patients. Syncope may occur. Pregnancy & lactation.
Adverse Reactions
Inj site reactions (including pain, redness & swelling), fatigue. GI disorders. Adults, adolescents & childn ≥10 yr: Headache; malaise. Dizziness; nausea; fever ≥37.5°C, inj site reactions (eg, inj site mass & abscess sterile). Childn 4-9 yr: Irritability; somnolence. Anorexia; headache; diarrhoea, vomiting; fever ≥37.5°C (including fever >39°C).
Drug Interactions
Adequate response may not be achieved in patients receiving immunosuppressive therapy.
MIMS Class
Vaccines, Antisera & Immunologicals
ATC Classification
J07AJ52 - pertussis, purified antigen, combinations with toxoids ; Belongs to the class of pertussis bacterial vaccines.
Presentation/Packing
Form
Boostrix susp for inj
Packing/Price
0.5 mL x 1's
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