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Metoprolol CR (BETAZOK) should not be given during pregnancy and lactation unless its use is considered essential. β-blockers may cause side effects, e.g. bradycardia, in the fetus and in the newborn and breast-fed infant.
The amount of metoprolol ingested via breast milk, however, seems to be negligible as regards β-blocking effect in the infant if the mother is treated with metoprolol in doses within the normal therapeutic range.
