HTN 100-200 mg daily, as a single dose in the morning or in divided doses (morning & evening). If needed, other antihypertensives may be added. Angina pectoris, cardiac arrhythmias 100-200 mg daily in divided doses (morning & evening). If needed, other antianginal or other antiarrhythmics may be added. Maintenance treatment after MI 200 mg daily in divided doses (morning & evening). Functional heart disorders w/ palpitations 100 mg once daily in the morning, may be increased to 200 mg if needed. Migraine prophylaxis 100-200 mg daily in divided doses (morning & evening). Hyperthyroidism 150-200 mg daily in 3-4 doses, may increase dose if needed.
View Betaloc overdosage for action to be taken in the event of an overdose.
Administration
Should be taken on an empty stomach.
Contraindications
Hypersensitivity metoprolol or to other β-blockers. AV block of 2nd or 3rd degree; unstable decompensated cardiac failure (pulmonary oedema, hypoperfusion or hypotension), continuous or intermittent inotropic therapy; sinus bradycardia, sick-sinus syndrome, cardiogenic shock; severe peripheral arterial circulatory disorder. Suspected acute MI w/ heart rate <45 beats/min, P-Q interval >0.24 sec or systolic BP <100 mmHg.
Concomitant use w/ verapamil-type Ca antagonists. Asthma. Risk of interfering w/ carbohydrate metabolism or masking hypoglycemia. Patient w/ heart failure should have their decompensation treated before & during treatment. May aggravate preexisting AV conduction disorder of moderate degree; symptom of peripheral arterial circulatory disorders. Patients who develop increasing bradycardia; may aggravate symptoms of peripheral arterial circulatory disorders; pheochromocytoma. Avoid abrupt w/drawal. Patients w/ known ischemic heart disease. Do not stop in patients undergoing surgery. Avoid acute initiation of high doses to patients undergoing non-cardiac surgery. Anaphylactic shock. May impair ability to drive or operate machinery. Pregnancy & lactation.
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