Adult 500 mg as single dose for 3 days. Alternatively, may give initial dose of 500 mg followed by 250 mg daily for 4 days.
Uncomplicated genital infections caused by Chlamydia trachomatis & chancroid 1 g as single dose.
Uncomplicated gonorrhea 2 g as single dose.
Granuloma inguinale Initially 1 g followed by 500 mg daily or 1 g once a wk for 3 wk until all lesions have completely healed.
Prophylaxis of disseminated MAC infections 1.2 g once a wk.
Treatment or secondary prophylaxis 500 mg once daily w/ other antimycobacterials.
Mild or moderate typhoid 500 mg once daily for 7 days.
Childn >45 kg Usual adult dose.
Acute otitis media 30 mg/kg as single dose.
Pharyngitis or tonsillitis Childn >2 yr12 mg/kg once daily for 5 days.
Prophylaxis of disseminated MAC infections 20 mg/kg (max: 1.2 g) once wkly or 5 mg/kg (max: 250 mg) once daily.
Treatment of disseminated MAC infections 10-12 mg/kg (max: 500 mg) once daily w/ other antimycobacterials.
Childn ≥6 mth Prevention of secondary case of group A streptococcal infection in penicillin allergic childn 12 mg/kg (max: 500 mg) once daily for 5 days.
Mild to moderate typhoid 10 mg/kg once daily for 7 days.
Infant & childn >6 mth 10 mg/kg once daily for 3 days, or initial dose of 10 mg/kg followed by 5 mg/kg daily for 4 days.
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