Axibin Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Doxorubicin HCl

Indications/Uses

Malignant lymphomas (Hodgkin's & non-Hodgkin's lymphomas, lymphoma sarcoma); gastric, hepatic, colorectal & pancreatic carcinoma; acute myeloplastic leukemia; soft tissue & osteogenic sarcomas; breast, ovarian, lung, bronchogenic & bladder carcinoma; Wilms' carcinoma.

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Dosage/Direction for Use

Monotherapy: 60-75 mg/m² every 3 wk. In combination w/ other antitumor agents w/ overlapping toxicity: 30-40 mg/m² every 3 wk.

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Overdosage

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Contraindications

Hypersensitivity. Cardiac failure or preexisting heart disease. Pregnancy & lactation.

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Special Precautions

Hepatic & renal failure. Monitor patients w/ fetal infections, bone marrow depression, chickenpox. Infection & bleeding tendency. Do not administer via IM or SC. Avoid intraperitoneal. Elderly. Childn.

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Use In Pregnancy & Lactation

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Adverse Reactions

Supraventricular tachycardia, arrhythmia, abdominal pain, ECG changes; anemia, bleeding, leukocytopenia, thrombocytopenia; fever, chills, urticaria, anaphylaxis; hepatic impairment; proteinuria; acute nausea, vomiting, mucositis, anorexia, diarrhea; reversible complete alopecia; fatigue, headache; cystic stimulation symptoms (oliguria, urodynia, urocystitis, hematuria); pneumothorax; blennophthalmia, epiphora, amenorrhea, aspermia.

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Drug Interactions

May potentiate toxicity of other anticancer agents. Exacerbates cyclophosphamide-induced hemorrhagic cystitis & enhances hepatotoxicity of 6-mercaptopurine.

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Storage

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Description

View Axibin description for details of the chemical structure and excipients (inactive components).

Action

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MIMS Class

Cytotoxic Chemotherapy

ATC Classification

L01DB01 - doxorubicin ; Belongs to the class of cytotoxic antibiotics, anthracyclines and related substances. Used in the treatment of cancer.

Regulatory Classification

Presentation/Packing

Form

Axibin inj 10 mg/5 mL

Packing/Price

1's

Form

Axibin inj 50 mg/25 mL

Packing/Price

1's

Axibin

doxorubicin

Manufacturer:

Korea United Pharma

Distributor:

Qualimed