CYP3A4 inhibitors eg, grapefruit juice, fibric acid derivatives (gemfibrozil, fenofibrate, other fibrates, niacin), macrolides (erythromycin, clarithromycin), immunosuppressants (cyclosporine), azole antifungals (itraconazole, ketoconazole), PIs (nelfinavir, lopinavir, ritonavir, saquinavir), antidepressants, nefazodone; CYP3A4 inducers eg, efavirenz, rifampin; colestipol; digoxin; OCs & HRT eg, norethindone, ethinylestradiol; Al- & Mg-containing antacids; diltiazem; fusidic acid.