Potential to enhance effect of certain antihypertensives. Sedation w/ alcohol or other CNS medicinal products. Concomitant use w/ medicinal products known to cause QT prolongation or electrolyte imbalance. Quinidine & other CYP2D6 inhibitors (eg, fluoxetine & paraxotine). Ketoconazole & other CYP3A4 inhibitors (eg, itraconazole & HIV PIs). Modest increase in aripiprazole conc w/ weak inhibitors of CYP3A4 (eg, diltiazem or escitalopram) or CYP2D6. Lower C
max & AUC w/ carbamazepine & other CYP3A4 inducers. Other potent inducers of CYP3A4 (eg, rifampicin, rifabutin, phenytoin, phenobarb, primidone, efavirenz, nevirapine & St. John's wort). Increase aripiprazole conc w/ other serotogenic eg, SSRI/SNRI.
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