Initial test dose: 0.1 mg/kg IV for suspected increased sensitivity. IVAdult 0.3-1.1 mg/kg w/ usual range of 20 mg up to max total of 100 mg. Infant<1 yr 2 mg/kg. Childn 1-12 yr 1 mg/kg. IM 3-4 mg/kg, max: 150 mg. Infant 4-5 mg/kg. Older childn 4 mg/kg, max 150 mg.
Atypical plasma cholinesterase. Patients w/ burns, massive trauma, renal impairment, severe long-lasting sepsis & severe hyperkalemia. Hypersensitivity to neuromuscular blockers. Family history of malignant hyperthermia.
Special Precautions
Reduced plasma cholinesterase activity. Avoid in patients w/ penetrating eye injury, raised IOP/glaucoma, those who will undergo incision of the eyeball. Caution use in patients w/ bone fractures, neuromuscular disorder, cardiac/resp disease. Childn.
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