Closely monitor during therapy in patients w/ bronchial asthma. Discontinue immediately if bronchospasm occurs; cutaneous & mucosal changes newly occur. Patients w/ history of ulcers, particularly if additional drugs that are known to irritate the mucous membranes of the GI tract are being taken. Perform appropriate measures (eg, drainage & aspiration) if the patient is unable to sufficiently expectorate. Avoid treatment for longer periods in patients w/ histamine intolerance. Pregnancy & lactation. Not to be used in childn <2 yr.