Severe liver damage. Concomitant use w/ ≥3 alcoholic drinks/day. Do not use w/ any other medicine containing paracetamol. Kidney or liver problems. Patient taking warfarin. Pregnancy & lactation.
Accelerated absorption w/ metoclopramide or domperidone. Reduced absorption w/ cholestyramine. May increase susceptibility to harmful effects to the liver w/ phenobarb. Increased INR & risk for bleeding w/ warfarin. Increases the anticoagulation effect of warfarin.
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