Discontinue immediately if allergic or anaphylactic type reactions occur; at the 1st clinical signs of CV overload, or increased BP, raised central venous pressure or pulmonary oedema. Must not be diluted w/ water for inj. Patients w/ congestive cardiac failure, HTN, oesophageal varices, pulmonary oedema, hemorrhagic diathesis, severe anaemia, renal or postrenal anuria. Ensure adequate hydration; carefully monitor patient to guard against circulatory overload & hyperhydration. Monitor electrolyte status. Controls of coagulation & haematocrit are necessary if comparatively large vol are to be replaced; ensure adequate substitution of other blood constituents (coagulation factors, electrolytes, platelets & erythrocytes). Hypervolaemia. Patients on controlled Na diet.