Hypersensitivity or allergy to propylene glycol or methyl ρ-hydroxybenzoate. Not recommended in patients unrecovered from sunburn. Avoid contact w/ eyes, lips, angles of nose, & mucous membranes. Patients w/ high levels of sun exposure & those w/ inherent sensitivity to sun. Reduce times of use or discontinue if hypersensitivity or severe troubles occur. Avoid other potentially irritating topical product (abrasive soaps/cleansers, soaps/cosmetics w/ strong drying effect, products w/ high conc of alcohol, astringents, spices, or limes). In case of applying other acne treatment drug eg, erythromycin (<4%), 1% clindamycin phosphate or benzoyl peroxide (<10%) in the morning, patients may use Adrylex jointly in the evening. Minimize exposure to sunlight including sunlamps. Pregnancy.