Actein

Actein

acetylcysteine

Manufacturer:

U-Liang Pharmaceutical

Distributor:

Endure Medical

Marketer:

Endure Medical
Concise Prescribing Info
Contents
Acetylcysteine
Indications/Uses
Resp affections characterized by thick & viscous hypersecretions due to acute & chronic bronchitis & its exacerbation, pulmonary emphysema, mucoviscidosis & bronchiectasis.
Dosage/Direction for Use
Adult 200 mg (2 sachets) bid-tid. Childn 100 mg (1 sachet) bid-qid according to age. Duration: Acute phase: 5-10 days. Chronic state: May be continued for several mth.
Administration
May be taken with or without food: Dissolve in a glass w/ small quantity of water & mix.
Contraindications
Hypersensitivity. Patients w/ phenylketonuria due to aspartame content. Childn <2 yr.
Special Precautions
Asthma; monitor patients w/ bronchial asthma during therapy. Discontinue treatment immediately if bronchospasm occur. Patient w/ history of peptic ulceration; histamine intolerance (long-term therapy). Concomitant administration of other medicines w/ known irritating effect on the gastric mucosa. Perform postural drainage & bronchoaspiration if patient is not able to effectively expectorate. Possible presence of sulfurous smell. Not to be mixed w/ other drugs. Contains sorbitol; not to be taken by patients w/ rare hereditary problems of fructose intolerance. Contains aspartame. May interfere w/ colorimetric assay method for salicylate measurement. May interfere w/ urine ketone test. Avoid use during or prior in pregnancy. Lactation.
Adverse Reactions
GI adverse events. Anaphylactic shock, anaphylactic/anaphylactoid reaction, bronchospasm, angioedema, rash & pruritus.
Drug Interactions
Reduction in cough reflex that could lead to bronchial secretions accumulation w/ antitussive drugs. Significant hypotension & enhanced temporal artery dilation w/ nitroglycerin. May result in subtherapeutic levels of carbamazepine. Not recommended to be dissolved w/ other drugs. Inactivation of antibiotics. Reduced effect w/ activated charcoal.
MIMS Class
Cough & Cold Preparations
ATC Classification
R05CB01 - acetylcysteine ; Belongs to the class of mucolytics. Used in the treatment of wet cough.
V03AB23 - acetylcysteine ; Belongs to the class of antidotes. Used to neutralize paracetamol overdose.
Presentation/Packing
Form
Actein granules for soln 100 mg
Packing/Price
(orange flavor) 1.5 g x 30 × 1's
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