Acotril Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Glimepiride

Indications/Uses

Type 2 DM.

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Dosage/Direction for Use

Starting dose: 1-2 mg daily, increased gradually by 1-2 mg daily at intervals of 1-2 wk. Maintenance dose: 1-4 mg/day. Max dose: 8 mg daily.

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Overdosage

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Administration

Should be taken with food: Take after the 1st main meal of the day. Do not skip meals.

Contraindications

Hypersensitivity. Impaired renal function. Not for the treatment of insulin-dependent DM. Ketoacidosis (w/ or w/o coma) & severe infection, trauma & other severe conditions. Pregnancy & lactation.

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Use In Pregnancy & Lactation

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Adverse Reactions

Hypoglycemia. Dizziness, asthenia, headache; nausea, vomiting, GI pain & diarrhea, allergic reactions w/ skin rashes & pruritus, hyponatremia; leukopenia, agranulocytosis, thrombocytopenia, hemolytic anemia, aplastic anemia, pancytopenia.

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Drug Interactions

May potentiate blood glucose-lowering effect w/ oral antidiabetics, insulin, ACE inhibitors, coumarin derivatives, quinolones, sulfonamides, tetracyclines, chloramphenicol, MAOIs, cyclophosphamide, fibrates, guanethidine, high dose pentoxifylline, salicylates, phenylbutazone, sulfinpyrazone & probenecid. May weaken blood glucose-lowering action w/ acetazolamide, corticosteroids, estrogens, progesterone, barbiturates, diuretics, epinephrine & other sympathomimetics, high dose of nicotinic acid, phenothiazines & phenytoin. May either potentiate or weaken the effect w/ alcohol, β-blockers, H₂-receptor antagonists, clonidine & reserpine.

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Storage

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Description

View Acotril description for details of the chemical structure and excipients (inactive components).

Action

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MIMS Class

Antidiabetic Agents

ATC Classification

A10BB12 - glimepiride ; Belongs to the class of sulfonylureas. Used in the treatment of diabetes.

Regulatory Classification

Presentation/Packing

Form

Acotril tab 2 mg

Packing/Price

100's (P1,569.62/box)

Acotril

glimepiride

Manufacturer:

Lloyd

Distributor:

PNSV Asia